Keep an eye on the weather, which is changing faster than predicted, and on the new diseases escaping or being made, even as we speak. It's a race between new tech and biosphere bankruptcy, I'd say.
Humans are pack animals. In Biblical times, the great market cities in Europe or the United States, people want to be with other people. And in a way, the more that we're isolated, whether we're living on farms and we're only talking to our cell phone, the greater the need we have for group experience. So while people are saying that no one is going to go shopping because it's just inconvenient, and it's not as easy as buying online, why are people going to concerts? Why are people going to museums? Why are they going to sporting events?