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There is no other city as vulgar and obscene as Osaka. We should celebrate the image and welcome the development of casinos and red-light districts to attract people.
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Charles Scott Sherrington
If we denote excitation as an end-effect by the sign plus (+), and inhibition as end-effect by the sign minus (-), such a reflex as the scratch-reflex can be termed a reflex of double-sign, for it develops excitatory end-effect and then inhibitory end-effect even during the duration of the exciting stimulus.
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