The greatest question of all is whether our experience on this planet is 'it' or whether there is something else. Things in the supernatural realm give support, strangely perhaps, to the things we take on faith.
Honestly, the essence of publishing hasn't changed. Since the days of the cave man carving stuff on the cave walls, people have wanted stories, and storytellers have wanted an audience. That is still the case. The changes are really a matter of format.